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【 Find orlistat powder supplier in china for weight loss 】

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Orlistat (CAS NO.96829-58-2) is a drug designed to treat obesity. It is mainly used for preventing the absorption of fats from the human diet, thereby reducing caloric intake. Besides, it is intended for use in conjunction with a physician-supervised reduced-calorie diet.

Item Requirements Test Results
Appearance while to off-while powder White powder
Identification HPLC retention time Conforms
Melting Point 42 ºC -45°C 42°C-44°C
Specific optical rotation -31.0°~-41.0° -36.0°
Purity by HPLC no less than 98.0% 98.5%
Total impurity no more than 2.0% 1.6%
Max Individual impurity no more than 0.5% 0.3%
Water content%(K&F) no more than 0.5% 0.1%
Residual solvents EtOH no more than 0.5% N.D
EtAC no more than 0.5% N.D
n-Heptane no more than 0.5% less than 0.1%
Residue on ignition less than 0.2% 0.10%
Heavy metals as Pb no more than 20ppm less than20ppm
Assay (HPLC) no less than 98.0% 99.60%
Conclusion Meets the Requirements

Orlistat is an internationally recognized new form of weight loss drug. Its commercial name is Sainike and first went on sale in New Zealand in 1998. Orlistat is a long-term and highly effective specific gastrointestinal lipase inhibitor, and it is insoluble in water, soluble in chloroform, and easily soluble in ethanol.
Orlistat can be used clinically to treat obesity. Usually, a dose of 120mg is taken three times a day within one hour of a meal. Weight loss begins to occur after two weeks of usage. It can be used continuously for 6-12 months, and its effects will cease to increase after daily dosage exceeds 400mg. This drug is suitable to be used in combination with a low-calorie diet by obese and overweight individuals, and it can also be used as long-term treatment for patients who have faced weight-related risk factors. Orlistat has a long-term weight-control effect that reduces and maintains weight and prevents against rebounding. Using Orlistat can lower the occurrences of weight-related risk factors and diseases, including hypercholesterolemia, type-2 diabetes, impaired glucose tolerance, hyperinsulinemia, and hypertension, and it can reduce the fat content in organs. Orlistat also adjusts blood lipid levels: it can decrease serum triglycerides (TG) and low density lipoprotein cholesterol (LDL-C), and it can increase the ratio of high density lipoproteins to low density lipoproteins in obese patients.

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